Drug Metab Dispos. 2008 Dec 12 Talakad JC, Kumar S, Halpert JR. University of California San Diego. Cytochrome P450 (CYP) 2B6 metabolizes a number of clinically relevant drugs and is one of the most highly polymorphic human P450 enzymes, with the Lys(262)–>Arg substitution being especially common in several genetic variants. Therefore, K262R (2B6*4) was created [...]
Filed under: Cytochrome P450, Personalized Medicine, Pharmacogenetics | Tagged: Cytochrome, Cytochrome P450, cytochromes, Personalized Medicine, Pharmacogenetics | 1 Comment »
