COMMENT: The drug interactions of oral contraceptives (OCs) are quite complex. They are both a victim to CYP3A4 inducers- leading to possible reduction of ethinyl estradiol concentration and pregnancy and to CYP3A inhibitors– leading to increased adverse effects. The ethinyl estradiol component of OCs has been shown to be P450 cytochromal inhibitors of CYP2C9, CYP2C19, [...]
Filed under: Cytochrome P450, Drug Interactions, Personalized Medicine | Leave a Comment »
