COMMENT: Only in the last year has a new allele of CYP2C19 been recognized. CYP2C19*17 is associated with ultrarapid metabolizer status. Omeprazole is not only a probe drug for this CYP, but it is a widely used PPI throughout the world. The fact that individual who are homozygotic for this allele will have 2.1-fold lower [...]
Filed under: Cytochrome P450, Personalized Medicine, Pharmacogenetics | Tagged: clopidogrel, CYP2C19, omeprazole, Personalized Medicine, Pharmacogenetics, pharmacokinetics | 1 Comment »
