COMMENT:: Although clinicians should be aware of potential drug interactions with the statins that are CYP3A4 substrates and potent CYP3A4 inhibitors, the real-life clinical importance of them may have been a bit obscured. This observational database provides evidence of the relative clinical insignificance of these combinations in terms of creatine kinase increases when compared to [...]
Filed under: Cytochrome P450, Drug Interactions, Personalized Medicine | Tagged: CYP3A4, Cytochrome P450, Drug Interactions, lovastatin, simvastatin | Leave a Comment »
