Dr Oesterheld’s Comment: It has been well established that women with breast cancer who may receive tamoxifen should receive genetic CYP2D6 testing. They may be in a group of individuals who will not receive benefit from tamoxifen because they are slow metabolizers and will not convert the pro-drug tamoxifen to the active metabolite endoxifen which [...]
Filed under: Cytochrome P450, Personalized Medicine, Pharmacogenetics | Leave a Comment »
