Cytochrome P450 2D6 genotype variation and venlafaxine dosage

Dr. Oesterheld’s comment: This study supports the value of genetic CYP2D6 testing when a patient on venlafaxine has difficulty tolerating a low dose (75Mg) of the drug. Mayo Clin Proc. 2007 Sep;82(9):1065-8. Cytochrome P450 2D6 genotype variation and venlafaxine dosage. McAlpine DE, O’Kane DJ, Black JL, Mrazek DA. Department of Psychiatry and Psychology, Mayo Clinic, [...]

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